Which of the given statement is correct about the mechanism of wate...

Which of the given statement is correct about the mechanism of water soluble hormones?

A. Hormones bind to their cytoplasmic receptors present in the target cells.

B. The hormone-receptor complex alters the gene expression.

C. Hormones serve as the first messenger and cause the production of a second messenger.

D. The newly formed proteins produce a physiological response.